GABA

gamma-Aminobutyric acid, or γ-aminobutyric acid /ˈɡæmə əˈmiːnoʊbjuːˈtɪrɪk ˈæsɪd/, or GABA/ˈɡæbə/, is the chief inhibitoryneurotransmitter in the developmentally mature mammalian central nervous system. Its principal role is reducing neuronal excitability throughout the nervous system. In humans, GABA is also directly responsible for the regulation of muscle tone.^[2]

gamma-Aminobutyric acid

Names
Preferred IUPAC name 4-Aminobutanoic acid
Identifiers
CAS Number	56-12-2
3D model (JSmol)	Interactive image
ChEBI	CHEBI:16865
ChEMBL	ChEMBL96
ChemSpider	116
DrugBank	DB02530
ECHA InfoCard	100.000.235
EC Number	200-258-6
IUPHAR/BPS	1067
KEGG	D00058
MeSH	gamma-Aminobutyric+Acid
PubChem CID	119
RTECS number	ES6300000
UNII	2ACZ6IPC6I
InChI InChI=1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7)  Key: BTCSSZJGUNDROE-UHFFFAOYSA-N  InChI=1/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7) Key: BTCSSZJGUNDROE-UHFFFAOYAC
SMILES C(CC(=O)O)CN
Properties
Chemical formula	C4H9NO2
Molar mass	103.120 g/mol
Appearance	white microcrystalline powder
Density	1.11 g/mL
Melting point	203.7 °C (398.7 °F; 476.8 K)
Boiling point	247.9 °C (478.2 °F; 521.0 K)
Solubility in water	130 g/100 mL
log P	−3.17
Acidity (pKa)	4.031 (carboxyl; H2O) 10.556 (amino; H2O)[1]
Hazards
Main hazards	Irritant, Harmful
Lethal dose or concentration (LD, LC):
LD50 (median dose)	12,680 mg/